Transforming Cancer Therapeutics

Fund details

Your project can include:

• experimental evaluation at laboratory scale
• use of in vitro and in vivo models to evaluate proof of concept or safety
• exploration of potential production mechanisms
• prototyping
• product development planning
• intellectual property protection
• a demonstration of clinical utility and effectiveness
• a demonstration of safety and efficacy including phase 1 and 2 clinical trials
• regulatory planning

Specific themes

• next generation immunotherapies and immunomodulatory drugs
• manipulation of the tumour microenvironment to promote immune responses against solid tumours
• novel therapeutics that consider the unique characteristics of paediatric or young people’s cancers
• clinical decision support tools to optimise therapeutic dosing for children and young people

Eligibility

Your project must:

• have total costs between £150,000 and £4 million
• not exceed a grant request of £2 million
• have at least 50% of the total project costs shared by the SMEs, if collaborative
• start by 1 Aug 2024
• end by 31 July 2026
• last between 6 and 24 months
• carry out all of its project work in the UK
• intend to exploit the results from or in the UK

Funding

Up to £10 million has been allocated to fund innovation projects in this competition. Funding will be in the form of a grant. You must not claim more than £2 million in grant against your total project costs. A minimum of 50% of your total eligible project costs must be incurred by SMEs, if collaborative.

For industrial research projects, you could get funding for your eligible project costs of:

• up to 70% if you are a micro or small organisation
• up to 60% if you are a medium-sized organisation
• up to 50% if you are a large organisation

For experimental development projects which are nearer to market, you could get funding for your eligible project costs of:

• up to 45% if you are a micro or small organisation
• up to 35% if you are a medium-sized organisation
• up to 25% if you are a large organisation